Short Communication

Molecular epidemiology of infectious bursal disease virus in Zambia

Christopher J. Kasanga, Tsuyoshi Yamaguchi, Hetron M. Munang’andu, Kenji Ohya, Hideto Fukushi
Journal of the South African Veterinary Association | Vol 84, No 1 | a908 | DOI: https://doi.org/10.4102/jsava.v84i1.908 | © 2013 Christopher J. Kasanga, Tsuyoshi Yamaguchi, Hetron M. Munang’andu, Kenji Ohya, Hideto Fukushi | This work is licensed under CC Attribution 4.0
Submitted: 24 July 2012 | Published: 28 October 2013

About the author(s)

Christopher J. Kasanga, Department of Veterinary Microbiology and Parasitology, Sokoine University of Agriculture, Tanzania and Laboratory of Veterinary Microbiology, Gifu University, Japan
Tsuyoshi Yamaguchi, Avian Zoonoses Center, Tottori University, Japan
Hetron M. Munang’andu, Department of Paraclinical Sciences, University of Zambia, Zambia
Kenji Ohya, Laboratory of Veterinary Microbiology, Gifu University, Japan
Hideto Fukushi, Laboratory of Veterinary Microbiology, Gifu University, Japan

Abstract

Nucleotide sequences of the VP2 hypervariable region (VP2-HVR) of 10 infectious bursal disease viruses detected in indigenous and exotic chickens in Zambia from 2004 to 2005 were determined. Phylogenetic analysis showed that the viruses diverged into two genotypes and belonged to the African very virulent types (VV1 and VV2). In the phylogenetic tree, strains in one genotype clustered in a distinct group and were closely related to some strains isolated in western Africa (VV1), with nucleotide similarities of 95.7%– 96.5%. Strains in the other genotype were clustered within the eastern African VV type (VV2), with nucleotide similarities of 97.3%– 98.5%. Both genotypes were distributed in the southern parts of Zambia and had a unique conserved amino acid substitution at 300 (E→A) in addition to the putative virulence marker at positions 222(A), 242(I), 256(I), 294(I) and 299(S). These findings represent the first documentation of the existence of the African VV-IBDV variants in both indigenous and exotic chickens in Zambia.

Keywords

No related keywords in the metadata.

Metrics

Total abstract views: 4208
Total article views: 11847

 

Crossref Citations

1. Characterization of field infectious bursal disease viruses in Zambia: evidence of co-circulation of multiple genotypes with predominance of very virulent strains
Racheal Mwenda, Katendi Changula, Bernard M. Hang’ombe, Nozyechi Chidumayo, Alfred S. Mangani, Titus Kaira, Ayato Takada, Aaron S. Mweene, Edgar Simulundu
Avian Pathology  vol: 47  issue: 3  first page: 300  year: 2018  
doi: 10.1080/03079457.2018.1449941

2. Prioritizing smallholder animal health needs in East Africa, West Africa, and South Asia using three approaches: Literature review, expert workshops, and practitioner surveys
Zoë Campbell, Paul Coleman, Andrea Guest, Peetambar Kushwaha, Thembinkosi Ramuthivheli, Tom Osebe, Brian Perry, Jeremy Salt
Preventive Veterinary Medicine  vol: 189  first page: 105279  year: 2021  
doi: 10.1016/j.prevetmed.2021.105279

3. Genetic evolution of infectious bursal disease virus in Senegal
Badji Alkaly, Amadou Diallo Alpha, Ducatez Mariette, Tall Lo Fatou, Mbengue Mbaye, Diouf Moussa, Samb Yacine, Diop Mariame, Modou, Thiongane Yaya, Luc Guerin Jean, Bada Alambedji Rianatou
Journal of Veterinary Medicine and Animal Health  vol: 8  issue: 12  first page: 237  year: 2016  
doi: 10.5897/JVMAH2016.0521

4. Molecular characterisation of infectious bursal disease virus in Namibia, 2017
Umberto Molini, Gottlieb Aikukutu, Juliet Kabajani, Siegfried Khaiseb, Giovanni Cattoli, William Dundon
Onderstepoort Journal of Veterinary Research  vol: 86  issue: 1  year: 2019  
doi: 10.4102/ojvr.v86i1.1676

5. Seasonal variations in health indices of free-ranging asymptomatic guinea fowls (Numida meleagris) in Zambia
King Shimumbo Nalubamba, Ntombi Basimbi Mudenda, Eugene Chisela Bwalya, Maxwell Masuku, Musso Munyeme, Hetron Mweemba Munang'andu
Asian Pacific Journal of Tropical Medicine  vol: 7  first page: S143  year: 2014  
doi: 10.1016/S1995-7645(14)60221-2

6. Molecular characterization of infectious bursal disease viruses detected in vaccinated commercial broiler flocks in Lusaka, Zambia
Kunda Ndashe, Edgar Simulundu, Bernard M Hang’ombe, Ladslav Moonga, Hirohito Ogawa, Ayato Takada, Aaron S Mweene
Archives of Virology  vol: 161  issue: 3  first page: 513  year: 2016  
doi: 10.1007/s00705-015-2690-x

7. Pathogenicity of Kenyan Infectious Bursal Disease Virus Isolates in Indigenous Chickens
W.U. Mutinda, P.G. Mbuthia, L.W. Njagi, L.C. Bebora, P.N. Nyaga
International Journal of Poultry Science  vol: 18  issue: 11  first page: 523  year: 2019  
doi: 10.3923/ijps.2019.523.529