Original Research

Blood pressure changes in dogs with babesiosis

L.S. Jacobson, R.G. Lobetti, T. Vaughan-Scott
Journal of the South African Veterinary Association | Vol 71, No 1 | a670 | DOI: https://doi.org/10.4102/jsava.v71i1.670 | © 2000 L.S. Jacobson, R.G. Lobetti, T. Vaughan-Scott | This work is licensed under CC Attribution 4.0
Submitted: 10 July 2000 | Published: 10 July 2000

About the author(s)

L.S. Jacobson,
R.G. Lobetti,
T. Vaughan-Scott,

Full Text:

PDF (160KB)

Abstract

Systemic arterial blood pressures were measured in 30 dogs with acute babesiosis, 10 each with mild uncomplicated, severe uncomplicated and complicated disease. Ten healthy dogs were used as controls. Hypotension was defined as more than 3 standard deviations below the control mean. Normal mean pressures (±SD) were: systolic arterial pressure 151 (±11) mm Hg, diastolic arterial pressure 89 (±8) mm Hg and mean arterial pressure 107 (±10) mmHg. Hypotension was the most frequent abnormality, and increased strikingly in incidence as disease severity increased, with 5/10 dogs in the complicated group being hypotensive for systolic, diastolic and mean arterial pressures, compared with 2/10 in the severe uncomplicated group and 0/10 in the mild uncomplicated group. Systolic, diastolic and mean arterial pressures in the complicated group and severe uncomplicated group, and systolic pressure in the mild uncomplicated group, were significantly lower than in the controls. There were no significant relationships between arterial pressures and age, pulse rate, respiratory rate, temperature, mucous membrane colour or haematocrit. There was a significant negative correlation between arterial pressures and white cell and immature neutrophil counts. Arterial pressures differed significantly between dogs that were clinically collapsed and those that were not, but not between survivors and non-survivors. Pulse pressure (systolic - diastolic) was low in 7/10 complicated, 1/10 mild uncomplicated, and 1/10 severe uncomplicated cases, and differed significantly between the complicated and control groups. The high incidence of hypotension in clinically severe babesiosis has important implications for therapy.

Keywords

Babesia Canis; Babesiosis; Blood Pressure; Canine; Dog; Hypotension; Shock

Metrics

Total abstract views: 3703
Total article views: 3388

 

Crossref Citations

1. Septic Shock Due to Babesiosis
Michael J. Dacey, Howard Martinez, Thomas Raimondo, Christopher Brown, John Brady
Clinical Infectious Diseases  vol: 33  issue: 5  first page: e37  year: 2001  
doi: 10.1086/322672

2. Septic shock in canine babesiosis
Vesna Matijatko, Ivana Kiš, Marin Torti, Mirna Brkljačić, Nada Kučer, Renata Barić Rafaj, Darko Grden, Tanja Živičnjak, Vladimir Mrljak
Veterinary Parasitology  vol: 162  issue: 3-4  first page: 263  year: 2009  
doi: 10.1016/j.vetpar.2009.03.011

3. CHANGES IN ECHOCARDIOGRAPHIC VARIABLES OF LEFT VENTRICULAR SIZE AND FUNCTION IN A MODEL OF CANINE NORMOVOLEMIC ANEMIA
TIM C. SPOTSWOOD, ROBERT M. KIRBERGER, LEE M.P.K. KOMA, PETER N. THOMPSON, DAVID B. MILLER
Veterinary Radiology & Ultrasound  vol: 47  issue: 4  first page: 358  year: 2006  
doi: 10.1111/j.1740-8261.2006.00154.x

4. Canine babesiosis
Masahiro YAMASAKI
Journal of the Japan Veterinary Medical Association  vol: 68  issue: 4  first page: 245  year: 2015  
doi: 10.12935/jvma.68.245

5. The dataset for the inflammatory response during experimental infection and treatment of dogs with Babesia rossi
Brogan Kim Atkinson, Peter Thompson, Estee Van Zyl, Amelia Goddard, Yolandi Rautenbach, Johan Petrus Schoeman, Varaidzo Mukorera, Andrew Leisewitz
Data in Brief  vol: 45  first page: 108475  year: 2022  
doi: 10.1016/j.dib.2022.108475

6. Doppler ultrasonographic changes in the canine kidney during normovolaemic anaemia
L.M. Koma, R.M. Kirberger, L. Scholtz
Research in Veterinary Science  vol: 80  issue: 1  first page: 96  year: 2006  
doi: 10.1016/j.rvsc.2005.04.002

7. Abdominal compartment syndrome in a dog with babesiosis
Kenneth E. Joubert, Patricia A. Oglesby, Justine Downie, Tania Serfontein
Journal of Veterinary Emergency and Critical Care  vol: 17  issue: 2  first page: 184  year: 2007  
doi: 10.1111/j.1476-4431.2006.00219.x

8. Systemic inflammatory responses in dogs experimentally infected with Babesia canis; a haematological study
Th.P.M. Schetters, J.A.G.M. Kleuskens, J. Van De Crommert, P.W.J. De Leeuw, A.-L. Finizio, A. Gorenflot
Veterinary Parasitology  vol: 162  issue: 1-2  first page: 7  year: 2009  
doi: 10.1016/j.vetpar.2009.02.012

9. NT-ProBNP and cardiac troponin I in virulent canine babesiosis
Remo Lobetti, Robert Kirberger, Ninette Keller, Frank Kettner, Eran Dvir
Veterinary Parasitology  vol: 190  issue: 3-4  first page: 333  year: 2012  
doi: 10.1016/j.vetpar.2012.07.021

10. Vaccination against canine babesiosis
Theo Schetters
Trends in Parasitology  vol: 21  issue: 4  first page: 179  year: 2005  
doi: 10.1016/j.pt.2005.02.006

11. Kinetics of the inflammatory response during experimental Babesia rossi infection of beagle dogs
B.K. Atkinson, P. Thompson, E. Van Zyl, A. Goddard, Y. Rautenbach, J.P. Schoeman, V. Mukorera, A. Leisewitz
Veterinary Parasitology  vol: 306  first page: 109717  year: 2022  
doi: 10.1016/j.vetpar.2022.109717

12. Metabolomics Insights into Salivary Profile in Dogs with Babesia canis Infection
Josipa Kuleš, Ivana Rubić, Dina Rešetar Maslov, Maša Efendić, Krešimir Martinković, Elizabeta Pongrac, Iva Šmit, Dalibor Potočnjak, Renata Barić Rafaj, Vladimir Mrljak
Biomolecules  vol: 15  issue: 4  first page: 520  year: 2025  
doi: 10.3390/biom15040520

13. Glucose, lactate, and pyruvate concentrations in dogs with babesiosis
Linda S. Jacobson, Remo G. Lobetti
American Journal of Veterinary Research  vol: 66  issue: 2  first page: 244  year: 2005  
doi: 10.2460/ajvr.2005.66.244

14. The South African form of severe and complicated canine babesiosis: Clinical advances 1994–2004
Linda S. Jacobson
Veterinary Parasitology  vol: 138  issue: 1-2  first page: 126  year: 2006  
doi: 10.1016/j.vetpar.2006.01.047

15. Nitric oxide metabolites in naturally occurring canine babesiosis
Linda S. Jacobson, Remo G. Lobetti, Pieter Becker, Fred Reyers, Tarquin Vaughan-Scott
Veterinary Parasitology  vol: 104  issue: 1  first page: 27  year: 2002  
doi: 10.1016/S0304-4017(01)00606-9

16. ABDOMINAL ULTRASONOGRAPHIC FINDINGS IN DOGS NATURALLY INFECTED WITH BABESIOSIS
EDUARDO FRAGA, JOSÉ DANIEL BARREIRO, ANA GOICOA, LUCIANO ESPINO, GEMMA FRAGA, ANDRÉS BARREIRO
Veterinary Radiology & Ultrasound  vol: 52  issue: 3  first page: 323  year: 2011  
doi: 10.1111/j.1740-8261.2010.01775.x

17. A prospective, randomized comparison of Oxyglobin (HB‐200) and packed red blood cell transfusion for canine babesiosis
Anthony B. Zambelli, Andrew L. Leisewitz
Journal of Veterinary Emergency and Critical Care  vol: 19  issue: 1  first page: 102  year: 2009  
doi: 10.1111/j.1476-4431.2009.00386.x

18. Mechanisms Involved in the Persistence of Babesia canis Infection in Dogs
Theo Schetters
Pathogens  vol: 8  issue: 3  first page: 94  year: 2019  
doi: 10.3390/pathogens8030094

19. Influence of normovolemic anemia on Doppler characteristics of the abdominal aorta and splanchnic vessels in Beagles
Lee M. Koma, Tim C. Spotswood, Robert M. Kirberger, Piet J. Becker
American Journal of Veterinary Research  vol: 66  issue: 2  first page: 187  year: 2005  
doi: 10.2460/ajvr.2005.66.187

20. Immunity against Babesia rossi infection in dogs vaccinated with antigens from culture supernatants
Th.P.M. Schetters, T. Strydom, D. Crafford, J.A.G.M. Kleuskens, J. van de Crommert, A.N. Vermeulen
Veterinary Parasitology  vol: 144  issue: 1-2  first page: 10  year: 2007  
doi: 10.1016/j.vetpar.2006.09.026

21. Combined Untargeted and Targeted Metabolomics Approaches Reveal Urinary Changes of Amino Acids and Energy Metabolism in Canine Babesiosis With Different Levels of Kidney Function
Josipa Kuleš, Ivana Rubić, Blanka Beer Ljubić, Petra Bilić, Renata Barić Rafaj, Mirna Brkljačić, Richard Burchmore, David Eckersall, Vladimir Mrljak
Frontiers in Microbiology  vol: 12  year: 2021  
doi: 10.3389/fmicb.2021.715701

22. Evidence of an acute phase response in dogs naturally infected with Babesia canis
Vesna Matijatko, Vladimir Mrljak, Ivana Kiš, Nada Kučer, Jadranka Foršek, Tanja Živičnjak, Željko Romić, Zoran Šimec, Jose Joaquin Ceron
Veterinary Parasitology  vol: 144  issue: 3-4  first page: 242  year: 2007  
doi: 10.1016/j.vetpar.2006.10.004

23. Cerebral babesiosis and acute respiratory distress syndrome in a dog
Thomas Daste, Marie‐Noelle Lucas, Marcel Aumann
Journal of Veterinary Emergency and Critical Care  vol: 23  issue: 6  first page: 615  year: 2013  
doi: 10.1111/vec.12114

24. Capillary and venous Babesia canis rossi parasitaemias and their association with outcome of infection and circulatory compromise
Marlies Böhm, Andrew L. Leisewitz, Peter N. Thompson, Johannes P. Schoeman
Veterinary Parasitology  vol: 141  issue: 1-2  first page: 18  year: 2006  
doi: 10.1016/j.vetpar.2006.05.002

25. Increased serum urea to creatinine ratio and its negative correlation with arterial pressure in canine babesiosis
Wojciech Zygner, Olga Gójska-Zygner
Acta Parasitologica  vol: 59  issue: 3  year: 2014  
doi: 10.2478/s11686-014-0273-8

26. Histological and ultrastructural studies of renal lesions in Babesia canis infected dogs treated with imidocarb
Á. Máthé, M. Dobos-Kovács, K. Vörös
Acta Veterinaria Hungarica  vol: 55  issue: 4  first page: 511  year: 2007  
doi: 10.1556/avet.55.2007.4.10

27. Hyponatraemia and syndrome of inappropriate antidiuretic hormone secretion in non-azotaemic dogs with babesiosis associated with decreased arterial blood pressure
Olga Gójska-Zygner, Justyna Bartosik, Paweł Górski, Wojciech Zygner
Journal of Veterinary Research  vol: 63  issue: 3  first page: 339  year: 2019  
doi: 10.2478/jvetres-2019-0045

28. Hyperaldosteronism and its association with hypotension and azotaemia in canine babesiosis
Olga Gójska-Zygner, Wojciech Zygner
Veterinary Quarterly  vol: 35  issue: 1  first page: 37  year: 2015  
doi: 10.1080/01652176.2014.981765

29. Assessing the welfare of dogs surgically sterilized during single day free community pet clinics in Kampala Metropolitan area, Central Uganda
Zozianne Hoareau, Lewis Ashabahebwa, William Lume, Kelvin Bwambale, Suzanne T. Millman, Dickson Stuart Tayebwa
Animal Welfare  vol: 35  year: 2026  
doi: 10.1017/awf.2026.10071

30. Clinical management of canine babesiosis
Ashley L. Ayoob, Susan G. Hackner, Jennifer Prittie
Journal of Veterinary Emergency and Critical Care  vol: 20  issue: 1  first page: 77  year: 2010  
doi: 10.1111/j.1476-4431.2009.00489.x

31. Influence of normovolemic anemia on Doppler characteristics of the abdominal aorta and splanchnic vessels in Beagles
Lee M. Koma, Tim C. Spotswood, Robert M. Kirberger, Piet J. Becker
American Journal of Veterinary Research  vol: 66  issue: 2  first page: 180  year: 2005  
doi: 10.2460/ajvr.2005.66.180

32. Electrocardiographic changes and cardiac pathology in canine babesiosis
Eran Dvir, Remo G Lobetti, Linda S Jacobson, Joyce Pearson, Piet J Becker
Journal of Veterinary Cardiology  vol: 6  issue: 1  first page: 15  year: 2004  
doi: 10.1016/S1760-2734(06)70060-1

33. The Mixed Acid-Base Disturbances of Severe Canine Babesiosis
Andrew L Leisewitz, Linda S Jacobson, Helio SA de Morais, Fred Reyers
Journal of Veterinary Internal Medicine  vol: 15  issue: 5  first page: 445  year: 2001  
doi: 10.1111/j.1939-1676.2001.tb01573.x