Short Communication

Effect of clenbuterol on growth, nitrogen and energy balances and endocrine status in food-restricted sheep : research communication

L.A. Cardoso, O. Taveira
Journal of the South African Veterinary Association | Vol 73, No 3 | a574 | DOI: https://doi.org/10.4102/jsava.v73i3.574 | © 2002 L.A. Cardoso, O. Taveira | This work is licensed under CC Attribution 4.0
Submitted: 06 July 2002 | Published: 06 July 2002

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L.A. Cardoso,
O. Taveira,

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Abstract

The aim of this study was to examine the effect of the b2-adrenoceptor clenbuterol on food-restricted sheep. Clenbuterol was administered as a dietary admixture (4 mg/ kg diet) to a group of male Serra da Estrela sheep (n = 6).The animals were housed individually in metabolic cages and fed for 45 days at 65 % of estimated requirement for energy maintenance. An untreated group with the same energy intake level was included as a control. Changes in body mass, nitrogen and energy balances and insulin, insulin-like growth factor (IGF-1), and triiodothyronine (T3) levels in the experimental animals were monitored. During the 4th week of the trial, clenbuterol-treated sheep showed increased mass gains, greater energy retention and serum IGF-1 levels and decreased T3 serum concentrations. This study showed that clenbuterol may induce a protective effect in sheep subjected to periods of food deprivation, based on the body mass and digestible energy effects manifested by treated animals.

Keywords

Clenbuterol; Food-Restriction; Sheep

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