Short Communication

Cryptococcus neoformans granuloma in the lung and spinal cord of a free-ranging cheetah (Acinonyx jubatus). A clinical report and literature review : clinical communication

I.R. Millward, M.C. Williams
Journal of the South African Veterinary Association | Vol 76, No 4 | a432 | DOI: https://doi.org/10.4102/jsava.v76i4.432 | © 2005 I.R. Millward, M.C. Williams | This work is licensed under CC Attribution 4.0
Submitted: 15 June 2005 | Published: 15 June 2005

About the author(s)

I.R. Millward,
M.C. Williams,

Full Text:

PDF (324KB)

Abstract

A 6-year-old, male, wild-born, free-ranging cheetah (Acinonyx jubatus) was evaluated for acute onset of progressive lameness in the right hind limb. Survey radiographs were unrewarding and myelography indicated an intramedullary compressive mass at the L3-L4 region. A fine needle aspirate of the lesion indicated the presence of Cryptococcus organisms. Necropsy confirmed the presence of granulomas (cryptococcoma) in the lung and the spinal cord (meningomyelitis) caused by Cryptococcus neoformans var. gattii. Cryptococcus neoformans is a yeast-like organism that is a potential pathogen to many species. Initial infection is thought to be of respiratory origin and then it commonly disseminates systemically from the nasal cavity or lungs to the skin, eyes and central nervous system in particular. The cheetah tested negative for both feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV), as have all the previously reported cheetah cases. C. neoformans is a non-contagious, opportunistic organism and is the most common systemic mycoses in domestic cats and the cheetah.

Keywords

Acinonyx Jubatus; Cheetah; Cryptococcoma; Cryptococcus Neoformans Var; Gattii; Meningomyelitis

Metrics

Total abstract views: 3584
Total article views: 3628

 

Crossref Citations

1. Important Mycoses of Wildlife: Emphasis on Etiology, Epidemiology, Diagnosis, and Pathology—A Review: PART 1
Iniobong Chukwuebuka Ikenna Ugochukwu, Chioma Inyang Aneke, Nuhu Abdulazeez Sani, Jacinta Ngozi Omeke, Madubuike Umunna Anyanwu, Amienwanlen Eugene Odigie, Remigius Ibe Onoja, Ohiemi Benjamin Ocheja, Miracle Oluchukwu Ugochukwu, Iasmina Luca, Olabisi Aminah Makanju
Animals  vol: 12  issue: 15  first page: 1874  year: 2022  
doi: 10.3390/ani12151874

2. First case of disseminated cryptococcosis in aGorilla gorilla
Alexander Mischnik, Julia Stockklausner, Nicole Hohneder, Henrik E. Jensen, Stefan Zimmermann, David E. Reuss, Volker Rickerts, Kathrin Tintelnot, Clemens Stockklausner
Mycoses  vol: 57  issue: 11  first page: 664  year: 2014  
doi: 10.1111/myc.12215

3. A case report of cryptococcosis in a captive Cape hyrax (Procavia capensis)
Niki SEDGHI MASOUD, Susumu IWAIDE, Natsumi KOBAYASHI, Daisuke NAKAGAWA, Miyuki ORITO, Nobuaki IWAHASHI, Tomoaki MURAKAMI
Journal of Veterinary Medical Science  vol: 86  issue: 6  first page: 619  year: 2024  
doi: 10.1292/jvms.24-0079

4. Cryptococcosis in domestic and wild animals: A review
Carolina dos Santos Bermann, Caroline Quintana Braga, Lara Baccarin Ianiski, Sônia de Avila Botton, Daniela Isabel Brayer Pereira
Medical Mycology  vol: 61  issue: 2  year: 2023  
doi: 10.1093/mmy/myad016

5. Feline Cryptococcosis
Sameer R Trivedi, Richard Malik, Wieland Meyer, Jane E Sykes
Journal of Feline Medicine and Surgery  vol: 13  issue: 3  first page: 163  year: 2011  
doi: 10.1016/j.jfms.2011.01.009

6. Global Molecular Epidemiology ofCryptococcus neoformansandCryptococcus gattii: An Atlas of the Molecular Types
Massimo Cogliati
Scientifica  vol: 2013  first page: 1  year: 2013  
doi: 10.1155/2013/675213

7. Cryptococcal granuloma of the the basal ganglia with fatal haemorrhage after stereotactic biopsy: case report
GengHuan Wang, HePing Shen, ZhengMin Chu, JianGuo Shen, YiFei Wang
British Journal of Neurosurgery  vol: 37  issue: 4  first page: 656  year: 2023  
doi: 10.1080/02688697.2018.1550190

8. Cryptococcus in Wildlife and Free-Living Mammals
Patrizia Danesi, Christian Falcaro, Laura J. Schmertmann, Luisa Helena Monteiro de Miranda, Mark Krockenberger, Richard Malik
Journal of Fungi  vol: 7  issue: 1  first page: 29  year: 2021  
doi: 10.3390/jof7010029