Original Research

Determination of an optimal dose of medetomidine-ketamine-buprenorphine for anaesthesia in the Cape ground squirrel (Xerus inauris)

K. E. Joubert, T. Serfontein, M. Scantlebury, M B Manjerovic, P. W. Bateman, M B Manjerovic, P. W. Bateman, N. C. Bennett, J. M. Waterman
Journal of the South African Veterinary Association | Vol 82, No 2 | a41 | DOI: https://doi.org/10.4102/jsava.v82i2.41 | © 2011 K. E. Joubert, T. Serfontein, M. Scantlebury, M B Manjerovic, P. W. Bateman, M B Manjerovic, P. W. Bateman, N. C. Bennett, J. M. Waterman | This work is licensed under CC Attribution 4.0
Submitted: 10 April 2011 | Published: 11 April 2011

About the author(s)

K. E. Joubert, Pharmacology, Department of Paraclinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa., South Africa
T. Serfontein, Anaesthesiology, Onderstepoort Academic Veterinary Hospital, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa., South Africa
M. Scantlebury, School of Biological Sciences, Queen’s University Belfast, Belfast BT9 7BL, UK. Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa., South Africa
M B Manjerovic, Department of Biology, University of Central Florida, Orlando, FL 32816-2368, USA., United States
P. W. Bateman, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa, South Africa
M B Manjerovic, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa, South Africa
P. W. Bateman, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa., South Africa
N. C. Bennett, Department of Zoology and Entomology, University of Pretoria, Pretoria 0002, South Africa., South Africa
J. M. Waterman, Department of Biological Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Canada

Full Text:

PDF (165KB)

Abstract

The optimal dose of medetomidine-ketamine-buprenorphine was determined in 25 Cape ground squirrels (Xerus inauris) undergoing surgical implantation of a temperature logger into the abdominal cavity. At the end of anaesthesia, the squirrels were given atipamezole intramuscularly to reverse the effects of medetomidine. The mean dose of medetomidine was 67.6±9.2 μg/kg, ketamine 13.6±1.9 mg/kg and buprenorphine 0.5±0.06 μg/kg. Induction time was 3.1 ± 1.4 min. This produced surgical anaesthesia for 21± 4.2 min. Atipamezole 232±92 μg/kg produced a rapid recovery. Squirrels were sternally recumbent in 3.5 ± 2.2 min.

Keywords

No related keywords in the metadata.

Metrics

Total abstract views: 4353
Total article views: 3852

 

Crossref Citations

1. Anesthetic effects of dexmedetomidine-ketamine-midazolam administered intramuscularly in five-striped palm squirrels (Funambulus pennantii)
David Eshar, Hugues Beaufrère
American Journal of Veterinary Research  vol: 80  issue: 12  first page: 1082  year: 2019  
doi: 10.2460/ajvr.80.12.1082

2. Seasonal Patterns of Body Temperature Daily Rhythms in Group-Living Cape Ground Squirrels Xerus inauris
Michael Scantlebury, Marine Danek-Gontard, Philip W. Bateman, Nigel C. Bennett, Mary-Beth Manjerovic, Kenneth E. Joubert, Jane M. Waterman, Mark Briffa
PLoS ONE  vol: 7  issue: 4  first page: e36053  year: 2012  
doi: 10.1371/journal.pone.0036053