Original Research

The pathology of subclinical infection of encephalitozoon cuniculi in canine dams producing pups with overt encephalitozoonosis

Elizabeth F. McInnes, C. G. Stewart
Journal of the South African Veterinary Association | Vol 62, No 2 | a1590 | DOI: https://doi.org/10.4102/jsava.v62i2.1590 | © 2020 Elizabeth F. McInnes, C. G. Stewart | This work is licensed under CC Attribution 4.0
Submitted: 31 August 2017 | Published: 30 June 1991

About the author(s)

Elizabeth F. McInnes, Department of Pathology, Faculty of Veterinary Science, Medical University of Southern Africa, South Africa
C. G. Stewart, Department of Infectious Diseases and Public Health, South Africa

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Abstract

The macroscopic, microscopic and clinical pathology and the serology of 2 clinically normal Staffordshire Bull Terrier bitches, both of whom produced pups with confirmed encephalitozoonosis, is described. Mild histopathological changes, similar to those seen in the infected pups, were observed. The spores of Encephalitozoon cuniculi were seen in the renal tubules of the kidney of one of the bitches. The serum urea concentrations of one of the bitches was elevated. A positive titre against E. cuniculi was obtained in both of the bitches. A 10-year-old girl who had close contact with one of the infected litters of pups, seroconverted to E. cuniculi. Her two siblings were serologically negative.

Keywords

Encephalitozoonosis; canine; dam; pathology; serology; Encephalitozoon cuniculi; human infection

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